About

Regener-Eyes® is a first in class, natural, biologic ophthalmic solution that is preservative free

Regener-Eyes® Ophthalmic Solution, Professional Strength and LITE contain naturally occurring cytokines, chemokines and growth factors  such as VEGF, TGFβ1, TGFβ3, EGF, IL-1Ra , PDGF, ST2, bFGF, KGF, GDF11, HC-HA/PTX3 (Pentraxin 3) (hyaluronic acid), and Collagen Types I, III, IV, V.  These proteins and growth factors are natural, necessary for cell function, overall health of the eye, and homeostasis.

Technology

Regener-Eyes® Ophthalmic Solution, Professional Strength and LITE products are manufactured utilizing d-MAPPS™ (derived–Multiple Allogeneic Proteins Paracrine Signaling) platform technology. This technology is engineered to stimulate stem cell communication without cell to cell contact. All cytokines have multiple functions and multiple target cells, as well as shared activities. When secreted in normal amounts, cytokines are important in normal homeostasis; when introduced in larger amounts, cytokines are important in cell recruitment, cell differentiation, and inflammation, all necessary in the healing process.

Proteins, Functions and their Constitution

Cytokines – anti-inflammatory – cytokines are a general term for all cell signaling protein molecules that function by attracting cells to inflammatory and/or infection sites. 

Chemokines – signal the immune system for healing potential – chemokines are specific cytokines  that function by attracting cells to inflammatory and/or infection sites. 

Growth Factors – may help trigger potential for cell regeneration – growth factors a subclass of cytokines that specifically stimulate the proliferation of cells, and hence, have the potential to improve wound healing through several mechanisms.

Hyaluronic Acid (HC-HA/PTX3) cushioning and moisturizing – HC-HA/PTX3 is a clear substance produced naturally by the body and is primarily found in skin, connective tissue and eyes. Its main function is to retain water and to keep tissues moisturized. It regulates several aspects of tissue repair including activation of inflammatory cells to enhance immune response.

Dosage and Administration 

Regener-Eyes® Ophthalmic Solution, Professional Strength and LITE: Instill one to four drops, one to four times per day in each eye, or as recommended by your Eye Care Professional (ECP).

Contact lenses should be removed prior to administration of Regener-Eyes® Professional Strength and LITE products. Contact lenses may be reinserted 15 minutes following administration of Regener-Eyes® Ophthalmic Solutions. 

The tip of the vial should not touch any surfaces including the eye to avoid contamination of the products and injury to the eye. Following each use, the screw cap should be placed on the vial and twisted to seal the ophthalmic solution vial. 

Safety

Regener-Eyes® Ophthalmic Solution, Professional Strength and LITE, are preservative free, acellular solutions produced by our proprietary patent protected processes to ensure the safety and bioactivity of both products. Regener-Eyes® Ophthalmic Solution has an excellent safety profile with no reported adverse events.

Each batch of Regener-Eyes® Ophthalmic Solution, Professional Strength and LITE are released based on a “Certificate of Analysis” and a “Certificate of Sterility” to ensure the quality and safety of both products.

How Supplied, Storage and Shelf Life

Regener-Eyes® Ophthalmic Solution, Professional Strength products must be refrigerated until use. Once opened, each vial must be kept refrigerated and used within 90 days. Regener-Eyes® Ophthalmic Solution,  Professional Strength has a shelf life of three (3) years when stored at refrigerated conditions.

Regener-Eyes® Ophthalmic Solution, LITE  can be stored at room temperature until use. Once opened, each vial can be stored at room temperature and used within 90 days. Regener-Eyes® Ophthalmic Solution, LITE has a shelf life of three (3) years when stored at room temperature.

About Us

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The Science

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